Publications

  1. Terry DS, Kolster RA, Quick M, LeVine MV, Khelashvili G, Zhou Z, Weinstein H, Javitch JA, Blanchard SC. A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport Nat Commun, Jan 2018 PMID: 29335402
  2. Morra G, Razavi AM, Pandey K, Weinstein H, Menon AK, Khelashvili G. Mechanisms of Lipid Scrambling by the G Protein-Coupled Receptor Opsin Structure, Dec 2017 PMID: 29290486
  3. Pandey K, Ploier B, Goren MA, Levitz J, Khelashvili G, Menon A. An engineered opsin monomer scrambles phospholipids Sci Rep., Nov 2017 PMID: 29196630
  4. Sylvester SJG, Lee MM, Ramirez AD, Lim S, Goldman MS, Aksay ERF. Population-scale organization of cerebellar granule neuron signaling during a visuomotor behavior Sci Rep., Nov 2017 PMID: 29176570
  5. LeVine MV, Cuendet MA, Razavi AM, Khelashvili G, Weinstein H. Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter Biophys J, Nov 2017 PMID: 29153319
  6. Vishwanathan A, Daie K, Ramirez AD, Lichtman JW, Aksay ERF, Seung HS. Electron Microscopic Reconstruction of Functionally Identified Cells in a Neural Integrator Curr Biol., Jul 2017 PMID: 28712570
  7. Weinstein AM. A mathematical model of the rat kidney: K+-induced natriuresis. Am J Physiol Renal Physiol, Jun 2017 PMID: 28179254
  8. Razavi AM, Khelashvili G, Weinstein H. A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter Nat Sci Rep, Jan 2017 PMID: 28059145
  9. Sahai MA, Davidson C, Khelashvili G, Barrese V, Dutta N, Weinstein H, Opacka-Juffry J. Combined in vitro and in silico approaches to the assessment of stimulant properties of novel psychoactive substances – The case of the benzofuran 5-MAPB J pnpbp, Nov 2016 PMID: 27890676
  10. Cuendet MA, Weinstein H, LeVine MV. The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems JCTC, Nov 2016 PMID: 27766843
  11. Khelashvili G, Schmidt SG, Shi L, Javitch JA, Gether U, Loland CJ, Weinstein H. Conformational Dynamics on the Extracellular Side of LeuT Controlled by Na+ and K+ Ions and the Protonation State of Glu290 J Biol Chem, Sep 2016 PMID: 27474737
  12. Veerappan A, Thompson M, Savage AR, Silverman ML, Chan WS, Sung B, Summers B, Montelione KC, Benedict P, Groh B, Vicencio AG, Peinado H, Worgall S, Silver RB. Mast cells and exosomes in hyperoxia-induced neonatal lung disease. AJP, Jun 2016 PMID: 27130530
  13. Zhao Y, Fay F, Hak S, Manuel Perez-Aguilar J, Sanchez-Gaytan BL, Goode B, Duivenvoorden R, de Lange Davies C, Bjørkøy A, Weinstein H, Fayad ZA, Pérez-Medina C, Mulder WJ. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nat Commun, Apr 2016 PMID: 27071376
  14. LeVine MV, Cuendet MA, Khelashvili G, Weinstein H. Allosteric Mechanisms of Molecular Machines at the Membrane: Transport by Sodium-Coupled Symporters Chem Rev, Feb 2016 PMID: 26892914
  15. LeVine MV, Khelashvili G, Shi L, Quick M, Javitch JA, Weinstein H. Role of Annular Lipids in the Functional Properties of Leucine Transporter LeuT Proteomicelles Biochem, Feb 2016 PMID: 26811944
  16. Arango-Lievano M, Sensoy O, Borie A, Corbani M, Guillon G, Sokoloff P, Weinstein H, Jeanneteau F. A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling Mol Cell Biol, Jan 2016 PMID: 26787837
  17. Stolzenberg S, Michino M, LeVine MV, Weinstein H, Shi L. Computational approaches to detect allosteric pathways in transmembrane molecular machines Biochim Biophys Acta., Jan 2016 PMID: 26806157
  18. Khelashvili G, Stanley N, Sahai MA, Medina J, LeVine MV, Shi L, De Fabritiis G, Weinstein H. Spontaneous Inward Opening of the Dopamine Transporter Is Triggered by PIP2‐Regulated Dynamics of the N‐Terminus ACS Chem Neurosci, Nov 2015 PMID: 26255829
  19. Billesbølle CB, Krüger MB, Shi L, Quick M, Li Z, Stolzenberg S, Kniazeff J, Gotfryd K, Mortensen JS, Javitch JA, Weinstein H, Loland CJ, Gether U. Substrate-induced Unlocking of the Inner Gate Determines the Catalytic Efficiency of a Neurotransmitter:Sodium Symporter J Biol Chem, Oct 2015 PMID: 26363074
  20. Khelashvili G, Weinstein H. Functional mechanisms of neurotransmitter transporters regulated by lipid-protein interactions of their terminal loops Biochim Biophys Acta., Sep 2015 PMID: 25847498
  21. Karlsen ML, Thorsen TS, Johner N, Ammendrup-Johnsen I, Erlendsson S, Tian X, Simonsen JB, Høiberg-Nielsen R, Christensen NM, Khelashvili G, Streicher W, Teilum K, Vestergaard B, Weinstein H, Gether U, Arleth L, Madsen KL. Structure of Dimeric and Tetrameric Complexes of the BAR Domain Protein PICK1 Determined by Small-Angle X-Ray Scattering Structure, Jul 2015 PMID: 26073603
  22. Weinstein AM. A mathematical model of rat proximal tubule and loop of Henle Am J Physiol Renal Physiol, May 2015 PMID: 25694479
  23. Weinstein AM. A mathematical model of the rat nephron: glucose transport. Am J Physiol Renal Physiol, May 2015 PMID: 25694480
  24. Lee MM, Arrenberg AB, Aksay ER. A structural and genotypic scaffold underlying temporal integration J Neurosci, May 2015 PMID: 25995475
  25. LeVine MV, Weinstein H. AIM for Allostery: Using the Ising Model to Understand Information Processing and Transmission in Allosteric Biomolecular Systems Entropy, May 2015 PMID: 26594108
  26. Khelashvili G, Doktorova M, Sahai MA, Johner N, Shi L, Weinstein H. Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2-containing membranes Proteins, May 2015 PMID: 25739722
  27. Stolzenberg S, Quick M, Zhao C, Gotfryd K, Khelashvili G, Gether U, Loland CJ, Javitch JA, Noskov S, Weinstein H, Shi L. Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters J Biol Chem, May 2015 PMID: 25869126
  28. Sensoy O, Weinstein H. A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1–PDZ-domain Biochim Biophys Acta., Apr 2015 PMID: 25592838
  29. Daie K, Goldman MS, Aksay ERF. Spatial patterns of persistent neural activity vary with the behavioral context of short-term memory Neuron, Feb 2015 PMID: 25661184
  30. Akyuz N, Georgieva ER, Zhou Z, Stolzenberg S, Cuendet MA, Khelashvili G, Altman RB, Terry DS, Freed JH, Weinstein H, Boudker O, Blanchard SC. Transport domain unlocking sets the uptake rate of an aspartate transporter Nature, Feb 2015 PMID: 25652997