Publications

  1. Huang J, Chen S, Zhang JJ, Huang XY. Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state Nat Struct Mol Biol, Apr 2013 PMID: 23435379
  2. Yang S, Huang FK, Huang J, Chen S, Jakoncic J, Leo-Macias A, Diaz-Avalos R, Chen L, Zhang JJ, Huang XY. Molecular mechanism of fascin function in filopodial formation J Biol Chem, Jan 2013 PMID: 23184945
  3. Yang S, Zhang JJ, Huang XY. Mouse models for tumor metastasis Methods in Molecular Biology, Jan 2013 PMID: 22956145
  4. Sayan Mondal, George Khelashvili, Lei Shi, and Harel Weinstein. The cost of living in the membrane: A case study of hydrophobic mismatch for the multi-segment protein LeuT Chem Phys Lip, In press
  5. Andersen OS. Perspectives on: Conformational coupling in ion channels J Gen Physiol, Dec 2012 PMID: 23183695
  6. Howery AE, Elvington S, Abraham SJ, Choi KH, Dworschak-Simpson S, Phillips S, Ryan CM, Sanford RL, Almqvist J, Tran K, Chew TA, Zachariae U, Andersen OS, Whitelegge J, Matulef K, Du Bois J, Maduke MC. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode Chem Biol, Nov 2012 PMID: 23177200
  7. Lewin N, Aksay E, Clancy CE. Computational modeling reveals dendritic origins of GABA(A)-mediated excitation in CA1 pyramidal neurons PLoS One, Oct 2012 PMID: 23071770
  8. Khelashvili G, Galli A, Weinstein H. Phosphatidylinositol 4,5-Biphosphate (PIP(2)) Lipids Regulate the Phosphorylation of Syntaxin N-Terminus by Modulating Both Its Position and Local Structure Biochem, Sep 2012 PMID: 22950482
  9. Haun S, Sun L, Hubrack S, Yule D, Machaca K. Phosphorylation of the rat Ins(1,4,5)P 3 receptor at T930 within the coupling domain decreases its affinity to Ins(1,4,5)P 3 Channels, Sep 2012 PMID: 22878752
  10. Khelashvili G, Albornoz PB, Johner N, Mondal S, Caffrey M, Weinstein H. Why GPCRs behave differently in cubic and lamellar lipidic mesophases J Am Chem Soc, Sep 2012 PMID: 22931253
  11. Stolzenberg S, Khelashvili G, Weinstein H. Structural Intermediates in a Model of the Substrate Translocation Path of the Bacterial Glutamate Transporter Homologue GltPh J Phys Chem B, May 2012 PMID: 22494242
  12. Demichelis F, Setlur SR, Banerjee S, Chakravarty D, Chen JY, Chen CX, Huang J, Beltran H, Oldridge DA, Kitabayashi N, Stenzel B, Schaefer G, Horninger W, Bektic J, Chinnaiyan AM, Goldenberg S, Siddiqui J, Regan MM, Kearney M, Soong TD, Rickman DS, Elemento O, Wei JT, Scherr DS, Sanda MA, Bartsch G, Lee C, Klocker H, Rubin MA. Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk PNAS, Apr 2012 PMID: 22496589
  13. Kim T, Lee KI, Morris P, Pastor RW, Andersen OS, Im W. Influence of hydrophobic mismatch on structures and dynamics of gramicidin a and lipid bilayers Biophys J, Apr 2012 PMID: 22500755
  14. Shan J, Khelashvili G, Mondal S, Mehler EL, Weinstein H. Ligand-Dependent Conformations and Dynamics of the Serotonin 5-HT(2A) Receptor Determine Its Activation and Membrane-Driven Oligomerization Properties PLoS Comp Biol, Apr 2012 PMID: 22532793
  15. Gravotta D, Carvajal-Gonzalez JM, Mattera R, Deborde S, Banfelder JR, Bonifacino JS, Rodriguez-Boulan E. The Clathrin Adaptor AP-1A Mediates Basolateral Polarity Dev Cell, Apr 2012 PMID: 22516199
  16. Mechler F, Victor JD. Dipole characterization of single neurons from their extracellular action potentials J Comput Neurosci, Feb 2012 PMID: 21667156
  17. McCoy JG, Nimigean CM. Structural correlates of selectivity and inactivation in potassium channels Biochim Biophys Acta., Feb 2012 PMID: 21958666
  18. Gottschalk RA, Hathorn MM, Beuneu H, Corse E, Dustin ML, Altan-Bonnet G, Allison JP. Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses PNAS, Jan 2012 PMID: 22223661
  19. Quick M, Shi L, Zehnpfennig B, Weinstein H, Javitch JA. Experimental conditions can obscure the second high-affinity site in LeuT Nat Struct Mol Biol, Jan 2012 PMID: 22245968
  20. Mondal S, Weinstein H, and Khelashvili G. Interactions of the Cell Membrane with Integral Proteins Comprehensive Biophysics, Vol. 9, Jan 2012
  21. Veerappan A, Reid AC, O'Connor N, Mora R, Brazin JA, Estephan R, Kameue T, Chen J, Felsen D, Seshan SV, Poppas DP, Maack T, Silver RB. Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model Am J Physiol Renal Physiol, Jan 2012 PMID: 21957176
  22. Frindt G, Palmer LG. Regulation of epithelial Na+ channels by adrenal steroids: mineralocorticoid and glucocorticoid effects Am J Physiol Renal Physiol, Jan 2012 PMID: 22012806
  23. Courjaret R, Machaca K. STIM and Orai in cellular proliferation and division Front Biosci, Jan 2012 PMID: 22201875
  24. McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW. iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS Science, Jan 2012 PMID: 22246778
  25. Wang L, Altman RB, Blanchard SC. Insights into the molecular determinants of EF-G catalyzed translocation RNA, Dec 2011 PMID: 22033333
  26. Deinhardt K, Kim T, Spellman DS, Mains RE, Eipper BA, Neubert TA, Chao MV, Hempstead BL. Neuronal growth cone retraction relies on proneurotrophin receptor signaling through rac Sci Signal, Dec 2011 PMID: 22155786
  27. Edvinsson JM, Shah AJ, Palmer LG. Potassium-dependent activation of Kir4.2 K+ channels J Physiol, Dec 2011 PMID: 22025665
  28. Weinstein H, Scarlata S. The correlation between multidomain enzymes and multiple activation mechanisms--the case of phospholipase Cβ and its membrane interactions Biochim Biophys Acta., Dec 2011 PMID: 21906583
  29. Altman RB, Terry DS, Zhou Z, Zheng Q, Geggier P, Kolster RA, Zhao Y, Javitch JA, Warren JD, Blanchard SC. Cyanine fluorophore derivatives with enhanced photostability Nat Methods, Nov 2011 PMID: 22081126
  30. Goldfine AM, Victor JD, Conte MM, Bardin JC, Schiff ND. Determination of awareness in patients with severe brain injury using EEG power spectral analysis Clin Neurophysiol, Nov 2011 PMID: 21514214
  31. Sun L, Yu F, Ullah A, Hubrack S, Daalis A, Jung P, Machaca K. Endoplasmic reticulum remodeling tunes IP₃-dependent Ca²+ release sensitivity PLoS One, Nov 2011 PMID: 22140486
  32. Weinstein AM. Potassium Excretion During Antinatriuresis: Perspective from a Distal Nephron Model Am J Physiol Renal Physiol, Nov 2011 PMID: 22114205
  33. Mondal S, Khelashvili G, Shan J, Andersen OS, Weinstein H. Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors Biophys J, Nov 2011 PMID: 22067146
  34. Snyder M, Huang XY, Zhang JJ. Signal transducers and activators of transcription 3 (STAT3) directly regulates cytokine-induced fascin expression and is required for breast cancer cell migration J Biol Chem, Nov 2011 PMID: 21937440
  35. Reid AC, Brazin JA, Morrey C, Silver RB, Levi R. Targeting cardiac mast cells: pharmacological modulation of the local renin-angiotensin system Curr Pharm Des, Nov 2011 PMID: 22103845
  36. Ingólfsson HI, Koeppe RE 2nd, Andersen OS. Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties FEBS Lett, Oct 2011 PMID: 21896274
  37. Budkevich T, Giesebrecht J, Altman RB, Munro JB, Mielke T, Nierhaus KH, Blanchard SC, Spahn CM. Structure and dynamics of the mammalian ribosomal pretranslocation complex Mol Cell, Oct 2011 PMID: 22017870
  38. Han DS, Golebiewska U, Stolzenberg S, Scarlata SF, Weinstein H. A dynamic model of membrane-bound phospholipase Cβ2 activation by Gβγ subunits Mol Pharmacol, Sep 2011 PMID: 21693623
  39. Capetillo-Zarate E, Gracia L, Yu F, Banfelder JR, Lin MT, Tampellini D, Gouras GK. High-Resolution 3D Reconstruction Reveals Intra-Synaptic Amyloid Fibrils Am J Pathol, Sep 2011 PMID: 21925470
  40. Victor JD, Drover JD, Conte MM, Schiff ND. Mean-field modeling of thalamocortical dynamics and a model-driven approach to EEG analysis PNAS, Sep 2011 PMID: 21368177
  41. Wang L, Guo D, Xing B, Zhang JJ, Shu HB, Guo L, Huang XY. Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization J Biol Chem, Sep 2011 PMID: 21771786
  42. Ingólfsson HI, Andersen OS. Alcohol's effects on lipid bilayer properties Biophys J, Aug 2011 PMID: 21843475
  43. Greisen P Jr, Lum K, Ashrafuzzaman M, Greathouse DV, Andersen OS, Lundbæk JA. Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling PNAS, Aug 2011 PMID: 21768343
  44. Evans SF, Irmady K, Ostrow K, Kim T, Nykjaer A, Saftig P, Blobel C, Hempstead BL. Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation J Biol Chem, Aug 2011 PMID: 21730062
  45. Yao Q, Li H, Liu BQ, Huang XY, Guo L. SUMOylation-regulated protein phosphorylation, evidence from quantitative phosphoproteomics analyses J Biol Chem, Aug 2011 PMID: 21685386
  46. Miri A, Daie K, Arrenberg AB, Baier H, Aksay E, Tank DW. Spatial gradients and multidimensional dynamics in a neural integrator circuit Nat Neurosci, Aug 2011 PMID: 21857656
  47. Rusinova R, Herold KF, Sanford RL, Greathouse DV, Hemmings HC Jr, Andersen OS. Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery J Gen Physiol, Aug 2011 PMID: 21788612
  48. Frindt G, Houde V, Palmer LG. Conservation of Na+ vs. K+ by the rat cortical collecting duct Am J Physiol Renal Physiol, Jul 2011 PMID: 21454253
  49. Glomski K, Monette S, Manova K, De Strooper B, Saftig P, Blobel CP. Deletion of Adam10 in endothelial cells leads to defects in organ-specific vascular structures Blood, Jul 2011 PMID: 21652679
  50. Aaker GD, Gracia L, Myung JS, Borcherding V, Banfelder JR, D'Amico DJ, Kiss S. Volumetric three-dimensional reconstruction and segmentation of spectral-domain OCT Ophthalmic Surg Lasers Imaging, Jul 2011 PMID: 21790107
  51. Haller A, Rieder U, Aigner M, Blanchard SC, Micura R. Conformational capture of the SAM-II riboswitch Nat Chem Biol, Jun 2011 PMID: 21532598
  52. Ingólfsson HI, Li Y, Vostrikov VV, Gu H, Hinton JF, Koeppe RE 2nd, Roux B, Andersen OS. Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. I: molecular dynamics simulations J Phys Chem B, Jun 2011 PMID: 21574563
  53. Vostrikov VV, Gu H, Ingólfsson HI, Hinton JF, Andersen OS, Roux B, Koeppe RE 2nd. Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. II: nuclear magnetic resonance experiments J Phys Chem B, Jun 2011 PMID: 21574558
  54. Zhao Y, Terry D, Shi L, Weinstein H, Blanchard SC, Javitch JA. Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homolog Nature, Jun 2011 PMID: 21516104
  55. Gu H, Lum K, Kim JH, Greathouse DV, Andersen OS, Koeppe RE 2nd. The membrane interface dictates different anchor roles for "inner pair" and "outer pair" tryptophan indole rings in gramicidin A channels Biochem, Jun 2011 PMID: 21539360
  56. Aaker GD, Gracia L, Myung JS, Borcherding V, Banfelder JR, D'Amico DJ, Kiss S. Three-dimensional reconstruction and analysis of vitreomacular traction: quantification of cyst volume and vitreoretinal interface area Arch Ophthalmol, Jun 2011 PMID: 21670354
  57. Quann EJ, Liu X, Altan-Bonnet G, Huse M. A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells Nat Immunol, May 2011 PMID: 21602810
  58. Machaca K. Ca(2+) signaling, genes and the cell cycle Cell Calcium, May 2011 PMID: 21809493
  59. Edvinsson JM, Shah AJ, Palmer LG. Kir4.1 K+ channels are regulated by external cations Channels, May 2011 PMID: 21532341
  60. Nimigean CM, Allen TW. Origins of ion selectivity in potassium channels from the perspective of channel block J Gen Physiol, May 2011 PMID: 21518829
  61. Andersen OS. Perspectives on: Ion selectivity J Gen Physiol, May 2011 PMID: 21518827
  62. Dunkle JA, Wang L, Feldman MB, Pulk A, Chen VB, Kapral GJ, Noeske J, Richardson JS, Blanchard SC, Cate JH. Structures of the bacterial ribosome in classical and hybrid states of tRNA binding Science, May 2011 PMID: 21596992
  63. Rosen AM, Victor JD, Di Lorenzo PM. Temporal coding of taste in the parabrachial nucleus of the pons of the rat J Neurophysiol, Apr 2011 PMID: 21307316
  64. Cheng WW, McCoy JG, Thompson AN, Nichols CG, Nimigean CM. Mechanism for selectivity-inactivation coupling in KcsA potassium channels PNAS, Mar 2011 PMID: 21402935
  65. Maretzky T, Evers A, Zhou W, Swendeman SL, Wong PM, Rafii S, Reiss K, Blobel CP. Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17 Nat Commun, Mar 2011 PMID: 21407195
  66. Sackin H, Nanazashvili M, Li H, Palmer LG, Yang L. Modulation of Kir1.1 inactivation by extracellular Ca and Mg Biophys J, Mar 2011 PMID: 21354393
  67. Stember JN, Andersen O. A one-dimensional continuum elastic model for membrane-embedded gramicidin dimer dissociation PLoS One, Feb 2011 PMID: 21326605
  68. Maretzky T, Zhou W, Huang XY, Blobel CP. A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17 Oncogene, Feb 2011 PMID: 20871631
  69. Cohen FS, Andersen OS. Cells on the MEND: exploring the role of lipidic forces in membrane trafficking J Gen Physiol, Feb 2011 PMID: 21242298
  70. Ohiorhenuan IE, Victor JD. Information-geometric measure of 3-neuron firing patterns characterizes scale-dependence in cortical networks J Comput Neurosci, Feb 2011 PMID: 20635129
  71. Banerjee S, Nimigean CM. Non-vesicular transfer of membrane proteins from nanoparticles to lipid bilayers J Gen Physiol, Feb 2011 PMID: 21282400
  72. Miri A, Daie K, Burdine RD, Aksay E, Tank DW. Regression-based identification of behavior-encoding neurons during large-scale optical imaging of neural activity at cellular resolution J Neurophysiol, Feb 2011 PMID: 21084686
  73. Chen JY, Victor JD, Di Lorenzo PM. Temporal coding of intensity of NaCl and HCl in the nucleus of the solitary tract of the rat J Neurophysiol, Feb 2011 PMID: 21106899
  74. Lugthart S, Figueroa ME, Bindels E, Skrabanek L, Valk PJ, Li Y, Meyer S, Erpelinck-Verschueren C, Greally J, Löwenberg B, Melnick A, Delwel R. Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1 Blood, Jan 2011 PMID: 20855866
  75. He Y, Liwo A, Weinstein H, Scheraga HA. PDZ Binding to the BAR Domain of PICK1 is Elucidated by Coarse-grained Molecular Dynamics J Mol Biol, Jan 2011 PMID: 21050858
  76. Yu F, Sun L, Courjaret R, Machaca K. Role of the STIM1 C-terminal domain in STIM1 clustering J Biol Chem, Jan 2011 PMID: 21220431
  77. Safdieh JE, Lin AL, Aizer J, Marzuk PM, Grafstein B, Storey-Johnson C, Kang Y. Standardized patient outcomes trial (SPOT) in neurology Med Educ Online, Jan 2011 PMID: 21249174
  78. Snyder M, Huang XY, Zhang JJ. Stat3 is essential for neuronal differentiation through direct transcriptional regulation of the Sox6 gene FEBS Lett, Jan 2011 PMID: 21094641
  79. Grafstein B. Subverting the hegemony of the synapse: complicity of neurons, astrocytes, and vasculature in spreading depression and pathology of the cerebral cortex Brain Res Rev, Jan 2011 PMID: 20888859
  80. Bisgaard H, Larsen MA, Mazier S, Beuming T, Newman AH, Weinstein H, Shi L, Loland CJ, Gether U. The binding sites for benztropines and dopamine in the dopamine transporter overlap Neuropharm, Jan 2011 PMID: 20816875
  81. Shan J, Javitch JA, Shi L, Weinstein H. The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter PLoS One, Jan 2011 PMID: 21298009
  82. Shi L, Weinstein H. Conformational Rearrangements to the Intracellular Open States of the LeuT and ApcT Transporters Are Modulated by Common Mechanisms Biophys J, Dec 2010 PMID: 21156121
  83. Munro JB, Wasserman MR, Altman RB, Wang L, Blanchard SC. Correlated conformational events in EF-G and the ribosome regulate translocation Nat Struct Mol Biol, Dec 2010 PMID: 21057527
  84. Yang L, Frindt G, Palmer LG. Magnesium modulates ROMK channel-mediated potassium secretion J Am Soc Nephrol, Dec 2010 PMID: 21030597
  85. Shan J, Weinstein H, Mehler EL. Probing the structural determinants for the function of intracellular loop 2 in structurally cognate g-protein-coupled receptors Biochem, Dec 2010 PMID: 21062002
  86. Duan Y, Weinstein AM, Weinbaum S, Wang T. Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells PNAS, Dec 2010 PMID: 21106755
  87. Machaca K. Ca(2+) signaling, genes and the cell cycle Cell Calcium, Nov 2010 PMID: 21084120
  88. Yu F, Sun L, Machaca K. Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis JCB, Nov 2010 PMID: 21041445
  89. Li Y, Andersen OS, Roux B. Energetics of double-ion occupancy in the gramicidin A channel J Phys Chem B, Nov 2010 PMID: 20939567
  90. Brandl K, Sun L, Neppl C, Siggs OM, Le Gall SM, Tomisato W, Li X, Du X, Maennel DN, Blobel CP, Beutler B. MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands PNAS, Nov 2010 PMID: 21041656
  91. Song W, Volosin M, Cragnolini AB, Hempstead BL, Friedman WJ. ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons J Neurosci, Nov 2010 PMID: 21084616
  92. Feinerman O, Jentsch G, Tkach KE, Coward JW, Hathorn MM, Sneddon MW, Emonet T, Smith KA, Altan-Bonnet G. Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response Mol Syst Biol, Nov 2010 PMID: 21119631
  93. Frindt G, Palmer LG. Effects of dietary K on cell-surface expression of renal ion channels and transporters Am J Physiol Renal Physiol, Oct 2010 PMID: 20702602
  94. Morrey C, Brazin J, Seyedi N, Corti F, Silver RB, Levi R. Interaction between sensory C-fibers and cardiac mast cells in ischemia/reperfusion: activation of a local renin-angiotensin system culminating in severe arrhythmic dysfunction J Pharmacol Exp Ther, Oct 2010 PMID: 20668055
  95. Tkacik G, Prentice JS, Victor JD, Balasubramanian V. Local statistics in natural scenes predict the saliency of synthetic textures PNAS, Oct 2010 PMID: 20923876
  96. Bach A, Stuhr-Hansen N, Thorsen TS, Bork N, Moreira IS, Frydenvang K, Padrah S, Christensen SB, Madsen KL, Weinstein H, Gether U, Strømgaard K. Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1 Org Biomol Chem, Oct 2010 PMID: 20668766
  97. Khelashvili G, Mondal S, Andersen OS, Weinstein H. Cholesterol modulates the membrane effects and spatial organization of membrane-penetrating ligands for G-protein coupled receptors J Phys Chem B, Sep 2010 PMID: 20804205
  98. Yu H, Mazzanti CL, Whitfield TW, Koeppe RE, Andersen OS, Roux B. A combined experimental and theoretical study of ion solvation in liquid N-methylacetamide J Am Chem Soc, Aug 2010 PMID: 20681718
  99. Koda K, Salazar-Rodriguez M, Corti F, Chan NY, Estephan R, Silver RB, Mochly-Rosen D, Levi R. Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells Circulation, Aug 2010 PMID: 20697027
  100. Lundbaek JA, Koeppe RE 2nd, Andersen OS. Amphiphile regulation of ion channel function by changes in the bilayer spring constant PNAS, Aug 2010 PMID: 20713738
  101. Accardi A, Picollo A. CLC channels and transporters: proteins with borderline personalities Biochim Biophys Acta., Aug 2010 PMID: 20188062
  102. Daily AE, Kim JH, Greathouse DV, Andersen OS, Koeppe RE 2nd. Polar groups in membrane channels: consequences of replacing alanines with serines in membrane-spanning gramicidin channels Biochem, Aug 2010 PMID: 20695525
  103. Schreiner R, Frindt G, Diaz F, Carvajal-Gonzalez JM, Perez Bay AE, Palmer LG, Marshansky V, Brown D, Philp NJ, Rodriguez-Boulan E. The absence of a clathrin adapter confers unique polarity essential to proximal tubule function Kidney Intl, Aug 2010 PMID: 20531453
  104. Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, Pin JP, Vriend G, Campagne F, Filizola M. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base Bioinf, Jul 2010 PMID: 20501551
  105. Claxton DP, Quick M, Shi L, de Carvalho FD, Weinstein H, Javitch JA, McHaourab HS. Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters Nat Struct Mol Biol, Jul 2010 PMID: 20562855
  106. Arredouani A, Yu F, Sun L, Machaca K. Regulation of store-operated Ca2+ entry during the cell cycle J Cell Sci, Jul 2010 PMID: 20554894
  107. Ohiorhenuan IE, Mechler F, Purpura KP, Schmid AM, Hu Q, Victor JD. Sparse coding and high-order correlations in fine-scale cortical networks Nature, Jul 2010 PMID: 20601940
  108. Snyder M, Huang XY, Zhang JJ. Stat3 directly controls the expression of Tbx5, Nkx2.5, and GATA4 and is essential for cardiomyocyte differentiation of P19CL6 cells J Biol Chem, Jul 2010 PMID: 20522556
  109. Pandarinath C, Victor JD, Nirenberg S. Symmetry breakdown in the ON and OFF pathways of the retina at night: functional implications J Neurosci, Jul 2010 PMID: 20668185
  110. Whitford PC, Geggier P, Altman RB, Blanchard SC, Onuchic JN, Sanbonmatsu KY. Accommodation of aminoacyl-tRNA into the ribosome involves reversible excursions along multiple pathways RNA, Jun 2010 PMID: 20427512
  111. B Grafstein. Axonal Transport: The Intracellular Traffic of the Neuron Comprehensive Physiology, Jun 2010
  112. Geggier P, Dave R, Feldman MB, Terry DS, Altman RB, Munro JB, Blanchard SC. Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome J Mol Biol, Jun 2010 PMID: 20434456
  113. Nirenberg S, Bomash I, Pillow JW, Victor JD. Heterogeneous response dynamics in retinal ganglion cells: the interplay of predictive coding and adaptation J Neurophysiol, Jun 2010 PMID: 20357061
  114. Coward J, Germain RN, Altan-Bonnet G. Perspectives for computer modeling in the study of T cell activation Cold Spring Harb Perspect Biol, Jun 2010 PMID: 20516137
  115. Blanchard SC, Cooperman BS, Wilson DN. Probing translation with small-molecule inhibitors Chem Biol, Jun 2010 PMID: 20609413
  116. Picollo A, Malvezzi M, Accardi A. Proton block of the CLC-5 Cl-/H+ exchanger JGP, Jun 2010 PMID: 20513761
  117. Sackin H, Nanazashvili M, Li H, Palmer LG, Walters DE. A conserved arginine near the filter of Kir1.1 controls Rb/K selectivity Channels, May 2010 PMID: 20458182
  118. Zhao Y, Terry D, Shi L, Weinstein H, Blanchard SC, Javitch JA. Single-molecule dynamics of gating in a neurotransmitter transporter homologue Nature, May 2010 PMID: 20463731
  119. Brass LF, Akabas MH, Burnley LD, Engman DM, Wiley CA, Andersen OS. Are MD-PhD programs meeting their goals? An analysis of career choices made by graduates of 24 MD-PhD programs Acad Med, Apr 2010 PMID: 20186033
  120. Chen L, Yang S, Jakoncic J, Zhang JJ, Huang XY. Migrastatin analogues target fascin to block tumour metastasis Nature, Apr 2010 PMID: 20393565
  121. Tanabe M, Nimigean CM, Iverson TM. Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB PNAS, Apr 2010 PMID: 20351243
  122. Pandarinath C, Bomash I, Victor JD, Prusky GT, Tschetter WW, Nirenberg S. A novel mechanism for switching a neural system from one state to another Front Comput Neurosci, Mar 2010 PMID: 20407612
  123. Hu Q, Victor JD. A set of high-order spatiotemporal stimuli that elicit motion and reverse-phi percepts J Vis, Mar 2010 PMID: 20377286
  124. Feng D, Kim T, Ozkan E, Light M, Torkin R, Teng KK, Hempstead BL, Garcia KC. Molecular and structural insight into proNGF engagement of p75NTR and sortilin J Mol Biol, Mar 2010 PMID: 20036257
  125. Zeynep H. Gümüş, Fernando Siso-Nadal, Ada Gjyrezi, Paul McDonagh, Iya Khalil, Paraskevi Giannakakou and Harel Weinstein. Quantification and analysis of combination drug synergy in high-throughput transcriptome studies IEEE Conf. Bioinf. Bioeng., Feb 2010
  126. Ingólfsson HI, Andersen OS. Screening for Small Molecules’ Bilayer- Modifying Potential Using a Gramicidin-Based Fluorescence Assay Assay Drug Devel Tech, Feb 2010 PMID: 20233091
  127. Guo D, Zhang JJ, Huang XY. A new Rac/PAK/GC/cGMP signaling pathway Mol Cell Biol, Jan 2010 PMID: 19937092
  128. Feldman MB, Terry DS, Altman RB, Blanchard SC. Aminoglycoside activity observed on single pre-translocation ribosome complexes Nat Chem Biol, Jan 2010 PMID: 19946275
  129. Figueroa ME, Lugthart S, Li Y, Erpelinck-Verschueren C, Deng X, Christos PJ, Schifano E, Booth J, van Putten W, Skrabanek L, Campagne F, Mazumdar M, Greally JM, Valk PJ, Löwenberg B, Delwel R, Melnick A. DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia Cancer Cell, Jan 2010 PMID: 20060365
  130. Thorsen TS, Madsen KL, Rebola N, Rathje M, Anggono V, Bach A, Moreira IS, Stuhr-Hansen N, Dyhring T, Peters D, Beuming T, Huganir R, Weinstein H, Mulle C, Strømgaard K, Rønn LC, Gether U. Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD PNAS, Jan 2010 PMID: 20018661
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