Critical Dissection of Scientific Data

Course Directors:Carl Blobel, MD, PhD, Olga Boudker, Ph.D., and Christopher Mason, PhD
When: Quarters III and IV annually
Time: Thursdays, 2:30 pm – 4:00 pm
Start Date: Thursday, March 3, 2016
Where: 1300 York Avenue, LC-504 Conference Room
Who: required for 1st PBSB students; 2nd year PBSB and Tri-I CBM students; Open to all WGSMS students

This course is required for all 1st and 2nd year PBSB graduate students, but is open to all WGSMS students. It is designed to train students in scientific presentation and critique. The structure is a formalized, in depth "journal club". Each 1st year student will choose a paper from a list provided by the Course Directors. Each 2nd year student will select a paper in their thesis field, subject to approval of the Course Directors. Each session will consist of a student formally presenting their selected paper to the class, which is expected to serve as a critical audience. The presentation should consist of an introduction of the relevant background literature, an objective presentation of the study, a subjective analysis/critique of the work, and suggestions for future work. Presentations by 2nd year students will be scheduled first, giving the 1st year students the opportunity to learn from their more senior colleagues. Grading will be based on presentation quality and contribution to constructive feedback.

Student GroupDateRoomFirst NameLast NamePaper Title
All3-MarLC-504ChirsMasonCourse Introduction
PBSB-2ndYr10-MarLC-504SagarChhangawalaAire controls gene expression in the thymic epithelium with ordered stochasticity
PBSB-2ndYr10-MarLC-504MichaelCrowleyEpithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.
PBSB-2ndYr10-MarLC-504JustinMorseGenetic code expansion in stable cell lines enables encoded chromatin modification
PBSB-2ndYr17-MarLC-504AsafPoranMutations driving CLL and their evolution in progression and relapse
PBSB-2ndYr17-MarLC-504MojdehShakibaPhosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
CBM-2ndYr17-MarLC-504Ashley StephenDoaneResponse and resistance to BET bromodomain inhibitors in triple-negative breast cancer
CBM-2ndYr31-MarLC-504JoshuaFassProtein conformational plasticity and complex ligand-binding kinetics explored by atomistic simulations and Markov models
CBM-2ndYr31-MarLC-504AndreaRizziAccurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field
CBM-2ndYr31-MarLC-504AndrewSchaumbergMicroenvironmental Heterogeneity Parallels Breast Cancer Progression: A HistologyÐGenomic Integration Analysis
CBM-2ndYr7-AprLC-504AlexaMcIntyreHepatitis C Virus RNA Functionally Sequesters miR-122
CBM-2ndYr7-AprLC-504JustinTorokMultiple regimes of robust patterns between network structure and biodiversity
CBM-2ndYr7-AprLC-504AngelaYuStructural imprints in vivo decode RNA regulatory mechanisms
PBSB-1stYr14-AprLC-504Shellie AnnDickDerivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells
PBSB-1stYr14-AprLC-504ItaiDoronResource limitation drives spatial organization in microbial groups
PBSB-1stYr28-AprLC-504GabrielFitzgeraldMutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair
PBSB-1stYr5-MayLC-504In SubHan

BB is the Belfer Research Building at 413 East 69th Street

LC-504 is at 1300 York Avenue